Cordaptive™ Cholesterol Drug - Merck & Co
Merck & Company announced that the Food and Drug Administration(FDA) had accepted it's New Drug Application for Cordaptive™ for a standard review. Cordaptive™, in earlier Phase I and II trials, has been shown to be effective in raising HDL cholesterol (HDL-C) levels and lowering LDL cholesterol (LDL-C) levels.
Cordaptive™ is a combination of extended release Niacin and laropiprant (to help with a known side-effect of Niacin called "flushing").
In early September, Merck also reported that Phase III trials of Cordaptive™ had reduced LDL-cholesterol (LDL-C) levels, increased HDL-cholesterol (HDL-C) levels and reduced triglyceride levels compared to placebo.
During the trial, Cordaptive™ was given both as a monotherapy and also added to patients currently using statin therapy. Patients given Cordaptive™ showed significantly less flushing than those receiving only the extended release Niacin.
Technorati Tags: Cholesterol LDL HDL laropiprantcordaptive
Cordaptive™ is a combination of extended release Niacin and laropiprant (to help with a known side-effect of Niacin called "flushing").
In early September, Merck also reported that Phase III trials of Cordaptive™ had reduced LDL-cholesterol (LDL-C) levels, increased HDL-cholesterol (HDL-C) levels and reduced triglyceride levels compared to placebo.
During the trial, Cordaptive™ was given both as a monotherapy and also added to patients currently using statin therapy. Patients given Cordaptive™ showed significantly less flushing than those receiving only the extended release Niacin.
Technorati Tags: Cholesterol LDL HDL laropiprantcordaptive
Labels: cholesterol, cordaptive, HDL, laropiprant, LDL
posted by Ken MacKenzie at 10:41 AM
6 Comments:
Cordaptive only increased HDL-C by 20% while niacins usually raise HDL-C by 25-40%. Why the differance?
What a nice blog you have here. I just happened to have a blog dedicated to all the info that I came across about Cholesterol as well,
http://lower-cholesterol-level.blogspot.com
It's still pretty new and I hope I can learn from you. If you got time please check it out at:
http://lower-cholesterol-level.blogspot.com
Have a nice day,
Thank you for posting the well informed blog. I've a website which has information on diabetes. You will get some valuable information there.
http://symtomsofdiabetes.adviceforum.org/
Hey,
We want to give you a chance to get free content for
your website. We will write the articles for you, all
you have to do is put them on your site, its
completely free to you.
If you ever run out of ideas on what to write about,
just come to myfitnesscontent.com and grab an article.
Each article is completely unique to your site and has
never been used or published before. This is a great
way to build your website with content, gain more
visitors and hopefully in the end, earn some type of
revenue off the site.
With each article you post on your site, we will also
build links to that article. This will allow your
articles to rank well in google, bringing more traffic
to your site.
Why do we do this? By us helping you, in the end it
will also help us. It's a win-win situation. Just take
a look at our site at http://www.myfitnesscontent.com
Thank you for your time!
Patti
This comment has been removed by the author.
Recently I came across your blog and I've been reading along. I thought I would leave my first comment. I do not know what to say except that I enjoyed reading. Nice blog. I'll keep visiting this blog often.
Post a Comment
<< Home